Mounting a USB connection to a chassis is very doable as well. This is what I did, I wired a micro usb cable to a standard USB connector mounted to a bread board and mounted to the unit.
The one on the far right is connected to the Axoloti, the one on the middle is connected to the extra Axo USB I/O for midi USB etc, and the one on the far left is connected to an Arduino due.
There is wiring on the inside that will power the Arduino Due and another board when switched on, The Arduino due USB connection is for when uploading sketches which isn't always needed.
There are 4 wires, 5v, GND, TX, RX.
If TX and RX is disconnected, only power goes through the usb to power your device, with TX and RX connected, well you can load your patches etc..
Important to note, if you intend to have multiple USB connections like I have, make sure that they are isolated from one another if you intend to use separate power supplies. But if it is all coming from the same supply, no issues..